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KMID : 1034720190110020173
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Journal of Neurosonology and Neuroimaging
2019 Volume.11 No. 2 p.173 ~ p.177
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Radiographic Features in a Patient Diagnosed with Neurosyphilis
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Park Yoon-Ah
Ann Jung-Woo
Jeon Seok-Hwi
Chung Eun-Joo
Kim Eung-Gyu
Park Joong-Hyun
Lee Seok-Mo
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Abstract
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The clinical features and brain magnetic resonance image (B-MRI) findings in neurosyphilis (NS) are highly varied. Cortical atrophy, especially involving the medial temporal lobes (MTL), is a remarkable radiographic feature, reported in B-MRI scans, in cases of NS presenting with severe cognitive impairments. The observed MTL atrophy is similar to the atrophy seen in neurodegenerative disorders such as Alzheimer’s disease (AD) or frontotemporal dementia (FTD). A fluorodeoxy- glucose-positron emission tomography (FDG-PET), used for the diagnosis of AD, commonly reveals global cortical hypometabolism, sparing basal ganglia and thalamus, in NS. We report a case of NS, with complex symptoms and bilateral MTL atrophy. FDG-PET imaging showed bilateral thalamic and right visual cortical glucose reduction, as well as diffuse cortical hypometabolism. This type of FDG-PET pattern is a new finding in the field of NS.
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KEYWORD
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Neurosyphilis, Magnetic resonance imaging, Mesial temporal lobes, Fluorodeoxyglucose F18 positron-emission tomography
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